Growth and nutritional status of children with homozygous sickle cell disease

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Growth and nutritional status of children with homozygous sickle cell disease.

BACKGROUND Poor growth and under-nutrition are common in children with sickle cell disease (SCD). This review summarises evidence of nutritional status in children with SCD in relation to anthropometric status, disease severity, body composition, energy metabolism, micronutrient deficiency and endocrine dysfunction. METHODS A literature search was conducted on the Medline/PUBMED, SCOPUS, SciE...

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Gall stones in Jamaican children with homozygous sickle cell disease.

Gall stones were detected by ultrasonography in 30 of 226 (13%) children with homozygous sickle cell disease aged 5-13 years participating in a cohort study from birth. Children with gall stones had significantly lower total haemoglobin and fetal haemoglobin and higher bilirubin concentrations, but further analysis showed that the apparent effects of haemoglobin and fetal haemoglobin concentrat...

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Brief report: parent perspectives of nutritional status and mealtime behaviors in children with sickle cell disease.

OBJECTIVE To qualitatively evaluate parent perspectives of eating problems, nutritional status, and the potential for nutritional intervention in children with sickle cell disease (SCD). METHODS Twenty parents of children with SCD participated in one of three focus groups to discuss questions related to the study's objectives. Three coders rated transcripts to identify common perceptions and ...

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Delayed adolescent growth in homozygous sickle cell disease.

Analysis of the growth abnormalities in sickle cell disease has been limited by the lack of longitudinal observations in individuals, and by an inability to quantitate the observed patterns. To investigate the timing and pattern of the adolescent growth spurt, longitudinal observations of height from the Jamaican cohort study were fitted to a mathematical model of growth (Preece-Baines model 1)...

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Weight status of children with sickle cell disease.

OBJECTIVE Historically, many children and adolescents with sickle cell disease (SCD) were underweight. Treatment advances like hydroxyurea have been associated with improved growth. We hypothesized that increased hemoglobin (Hb) levels would be associated with increased weight status of children with SCD. METHODS Investigators at 6 institutions conducted a retrospective chart review of all pa...

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ژورنال

عنوان ژورنال: Annals of Tropical Paediatrics

سال: 2008

ISSN: 0272-4936,1465-3281

DOI: 10.1179/146532808x335624